Thursday, February 2, 2012

2-1-12 Wednesday

MFR

quiz for friday
all steps in arm pull series
directions of scapula mvmt
reasons for uncoiling traps
sign of Thoracic Outlet syndrome and what techniques to relieve it
how do you know you're on psoas
4 activities of daily life that lengthens fascia or facilitates it
playtsma release steps
ex. credit: know what to do for certain aliments
anterior hip rot
LB
thoracic outlet
siatica
piraformis
neck pain, rom
itb
achilles


PHYS/PATH

Chapt 5 circulatory system function

delivers nutrients and o2
**interruption- ischemia: lack of o2 to cells
infarction: cell death due to long ischemia
clotting: interruption, hemophilia (can't clot), thrombopenia (not enough)
chemical balance- alkalosis (too much of alkaline), acidosis (too much of acid)

RBC- 120 day lifetime- spleen (like Florida) removes dead RBC
turnover rate 2million/sec
no nuclei, lots of hemoglobin (iron-based)
WBC, granular/agranular
platelets

Anemia: not enough rbc, insufficient o2- carrying capacity often sysptom of complication rather than freestanding problem
mostly women because of menstrual cycles
-cancer, infection, bone marrow-EPO-Kidney, blood leak somewhere
nutritional: iron deficient most common
iron needs vit C, copper, and stomach acid to absorb
iron holds on to o2 in blood cells-- decrease energy if lacking
-folic acid, b12 deficient- needed to form rbc
-pernicious anemian- inadequate vit b12
-hemorrhagic: blood loss,(ulcer, endometriosis), bleed out
-hemolytic: premature rbc death- splenomegaly, jaundice
-aplastic: suppressed bone marrow, shortage of all blood cells
autoimmune problem, renal failure
myelodysplastic- similar problem related to leukemia, myeloma
secondary - ulcers, kidney, hepatitis, leukemia, myeloma, lymphoma
S&S: pallor (pale), dyspnea, fatigue, increase heart rate

Embolism and Thrombus
embolism: traveling clot, usually brain, heart, lung
thrombus: lodged clot
platelets flow through circulatory system
clots form at site of damage, area of slow irregular blood flow
embolism travels until vessel is too small

Pulmonary embolism (PE) 650k/yr, 200k/yr die-lung
often related to DVT
risk factor: cardiovascular disease, recent trauma, bed/plane/car rest, surgery, preg, overweight, smoking (makes blood sticky), oral birth control
S&S: dyspnea, chest pain, looks like heart attack, cough with blood, increase risk of another event
loss of lung function- right side heart failure
Tx: thrombolytics (sometimes), anticoags, asprin, surgery
prevent: id risks, diet, life style, external compress leg

Arterial embolism- complication of atherosclerosis
when septum is intact, venous em travels to lung; with arterial..
the embolism can go anywhere except the lung.
such as:
-coronary artery (heart attack)
carotid/cervical (stroke)
renal artery (renal infarction)
femoral (mm infarction)
S&S: may be silent, involve sharp tingling pain, tissue damage and death
Tx: prophylactic anticoag

Hematoma: pooling of blood
-bruise: superficial capillaries (ecchymosis)
b/w mm sheath in brain- serious!
S&S: bruises- color, yellow/green is subacute

Hemophilia: inability to clot- genetic disorder
mostly men, carried on the x chromosome
Hemophilia A- 80%, clot factor XIII
Hemophilia B- 15% (christmas disease) factor IX
frequent nose bleeds, easily bruise
mm and nerve damage, more likely to get infection in blood, hep a,b, due to transfusions

Leukemia: cancer bone marrow
high wbc count, low number of platelets
myeloid or lymphoid (b cells, t cells) form bone marrow (abnormal shape and non-functioning wbc)
acute=aggressive, chronic=slow-grow
usually genetic mutation, exposure to toxin, radiation
4 main types:
AML: acute myelognous leukemia
CML: chronic myelognous leukemia
ALL: acute lymphocytic leukemia (most common cancer in kids)
CLL: chronic lymphocytic leukemia
S&S: suppressed production rbc-fatigue, anemia, easy bruise/bleed
diag: blood test, bone marrow biop, spinal tap
tx: chemo, radiation; tx can exacerbate symptoms

Malaria: parasitic infection of blood; vector-borne infection of blood cells
4 species of protozoa
spread by anopheles mosquitoes
90% of cases in Africa
life cycle of plasmodium:
-human bitten by female mosquitoes
-immature parasite introduced to bloodstream
-travels to liver, grows 6-9 days
-reenters bloodstream
-invades healthy rbc; feed on hemoglobin, replicates, ruptures and releases
S&S: fluctuation b/w fever and chills, anemia, jaundice; usually lasts 2 wks. you make it you live
often missed in U.S because not common
Tx: chloroquine- sincono bark?- beginning of homeopathy
prevent: prophylactic med

Myeloma: cancer bone marrow, specifically maturing B cells
multiple myeloma- holes in bones
usually older, 70, black men
flat bones more likely affected
secrete cytokines?
clocking osteoblast activity, stimulation of osteoclasts
**fragments in urine- Bence Jones Protein
kidney can be damaged
3 types:
multiple myeloma
solitary myeloma
extramedullary plastocytoma
S&S: silent early , bone pain, fracture, anemia, amyloidosis
diag: urinalysis, etc.

Sickle Cell Disease
autosomal recessive genetic condition (the little xx)
production of abnormal hemoglobin
most common in black, hispanic ...
S&S: inadequate o2 carrying - fatigue, short breath, pallor, jaundice, spleno....

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